I've just started A Heartbreaking Work of Staggering Genius. If you read this book, look for commentary in the most unlikely places. Like the copyright notice.
The first chapter dives right in to his mother's illness. It's clear where the "heartbreaking" part of the title might be going here. Well written, but I'm getting so depressed just reading and feeling this story (and knowing he lived it) that I'm not sure if I can keep reading.